About

Medsteer, with offices in Paris/France (HQ) and New York/USA, is a leading technology provider in the field of closed loop systems for the delivery of anaesthesia drugs. The company’s patented technologies focus on drug delivery solutions guided by the cortical activity of the patient.

Providing full automation and customization to the individual patient’s needs, closed loop anaesthesia opens up the way to a wide array of patient benefits associated with personalized medicine.

 

 

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EasyTIVA

EasyTIVA is a patented technology delivering full automation in the dosage of Propofol and Remifentinal. EasyTIVA is a mature technology validated by a broad and solid base of patient inclusions across numerous multicenter clinical trials (over 15 000). Both the induction and the regulation are supported for all patients and all surgeries.

Medsteer | Closed Loop Anesthesia | Easy Tiva
Medsteer | Closed Loop Anesthesia | Sensor

Non-invasive disposable sensors on the forehead of the patient provide real-time information about the cortical activity.

Medsteer | Closed Loop Anesthesia | BIS

Using the real-time cortical activity, the brain monitor delivers a depth of anaesthesia index. This is often represented by a value between 0 and 100.

EasyTIVA can operate with various brain monitor systems available on the market. Main suppliers are Medtronic, GE Healthcare.

Medsteer | Closed Loop Anesthesia | Easy Tiva

Leveraging the depth of anaesthesia index, EasyTIVA uses its patented algorithm to deliver full automation in the dosage of Propofol and Remifentanil during the entire surgery.

Medsteer | Closed Loop Anesthesia | Syringe

Using regular syringe pumps into a closed loop architecture, the exact amount of anesthesia drugs are delivered to the patient at the right time, duration and flowrate.

Publications

Since 2006 we have been engaged in 25 clinical trials around the world which have been documented in a large number of scientific publications.

2006

Feasibility of closed-loop titration of propofol guided by the Bispectral Index for general anaesthesia induction: a prospective randomized study.

European Journal of Anaesthesiology 23: 465–469

Titration of Propofol for Anesthetic Induction and Maintenance Guided by the Bispectral Index: Closed-loop versus Manual Control. A Prospective, Randomized, Multicenter Study.

Anesthesiology 104:686–95

2007

Closed-loop administration of propofol and remifentanil guided by the Bispectral Index in patient requiring an emergency lung volume reduction.

Paediatric Anaesthesia 17: 909-10

2008

Closed-Loop Control of Consciousness During Lung Transplantation: An Observational Study Journal of Cardiothoracic and Vascular

Anesthesia & Analgesia 22: 611-615

2009

Closed-loop titration of propofol and remifentanil guided by Bispectral Index in a patient with extreme gigantism.

Journal of Clinical Anesthesia 21: 542-4

2011

Closed-Loop Coadministration of Propofol and Remifentanil Guided by Bispectral Index: A Randomized Multicenter Study.  This publication was accompanied with an editorial

Anesthesia & Analgesia 112: 546-57

Occurrence of and risk factors for electroencephalogram burst suppression during Propofol–Remifentanil anaesthesia.

British Journal of Anaesthesia 107: 749–56

2012

Feasibility of Closed-loop Titration of Propofol and Remifentanil Guided by the Spectral M-Entropy Monitor.  This publication was accompanied with an editorial

Anesthesiology 116:286-95

2013

Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.

Intensive Care Medecine 39: 453-62

Automatic administration of propofol and remifentanil guided by the Bispectral index during rigid bronchoscopic procedures: a prospective randomized trial.

Canadian Journal of Anaesthesia 60: 881-887

2014

Automated titration of propofol and remifentanil decreases the anesthesiologist’s workload during vascular or thoracic surgery: a randomized prospective study.

Journal of Monitoring and Computing 28; 35-40

Comparison of different formulations of propofol: A randomized, double-blind trial using a closed-loop administration

Anesthesiology 120: 355-64

No clinically relevant sparing effect of Nitrous oxide on propofol-remifentanil anesthesia administered automatically guided by the Bispectral index. A randomized multicenter study.

British Journal of Anaesthesia 112: 842-51

Sparing effect of dexmedetomidine on propofol and remifentanil requirements during Bispectral Index   guided closed-loop controlled anesthesia: A double-blind, placebo-controlled study.

Anesthesia & Analgesia 118: 946-55

2015

Feasibility of Closed-loop Co-administration of Propofol and Remifentanil Guided by the Bispectral Index in Obese Patients: A Prospective Cohort Comparison.

British Journal of Anaesthesia 114: 605-14

Feasibility of Closed-loop Titration of Propofol and Remifentanil Guided by the Bispectral Monitor in Pediatric and Adolescent Patients: A Prospective Randomized Study.

Anesthesiology 122: 759-67

Team

The Medsteer founders, management team and board members combine internationally recognised anesthesiology expertise, with seasoned business leadership and an entrepreneurial mindset.

nicolas choussat

Nicolas Choussat

Chief Operating Officer

Dr. Thierry Chazot

Dr. Thierry Chazot

Chief Executive Officer

ngai liu

Dr. Ngai Liu

Chief Medical Officer

Contact

Medsteer SAS

40 Rue Worth

92151 Suresnes

E: info@medsteer.com

T: +33 183 62 78 18